Diabetic neuropathic pain: a role for testosterone metabolites - 0 views
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Nathan Goodyear on 24 Mar 14Great article. Really shows the depth of the androgens and androgen metabolites in diabetes and diabetic complications. In this study, DHT and its metabolis 3-alpha androstanediol were shown to reduce inflammation and pain associated with diabetic neuropathy. Significant reduction in inflammation signaling (IL-1beta, TNF-alpha) was seen as was potential neurodegenerative processes (glutamate release and astrocyte immunoreactivity).